Victor Arokia Doss, D (2017) Development of MLR and SVM aided QSAR Models to Identify common SAR of GABA Uptake Herbal Inhibitors used in the treatment of schizophrenia. Current Neuropharmacology, 15. pp. 1085-1092. ISSN 1 8 7 5 -6190

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Abstract

Alterations in GABAnergic system are implicated in the pathophysiology of
schizophrenia. Available antipsychotics that target GABA receptor form a desirable therapeutic
strategy in the treatment regimen of schizophrenia, unfortunately, suffer serious setback due to their
prolonged side effects. The present investigation focuses on developing QSAR models from the
biological activity of herbal compounds and their derivatives that promise to be alternative candidates
to GABA uptake inhibitors

Item Type: Article
Uncontrolled Keywords: Schizophrenia, Linear and non-linear QSAR models, MLR and SVM
Depositing User: Mr Team Mosys
Date Deposited: 10 Aug 2022 06:25
Last Modified: 10 Aug 2022 06:25
URI: http://ir.psgcas.ac.in/id/eprint/1439

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