Thangavelu, K (2016) d Tetrad Index a Promising Atherogenic Index in Acute Coronary Syndrome? International Journal of Scientific Study, 4 (8). pp. 73-77. ISSN 2321-595X
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Abstract
Introduction: Coronary heart disease (CHD) is expected to be the most important cause of death in India by 2020. Increased
concentration of atherogenic lipoprotein plays an important role in the development of atherosclerosis leading to premature
myocardial infarction. Etiology of CHD is multifactorial; a single biomarker is unlikely to provide information for coronary artery
disease occurrence. Hence, the present study is on the calculation of lipid tetrad index (LTI) in acute coronary syndrome (ACS).
Aims and Objectives: To estimate lipoprotein(a) (Lp[a]), lipid parameters, to calculate LTI, and to explore the diagnostic
importance of LTI as a risk factor in ACS.
Materials and Methods: Study group comprised 50 subjects admitted in the intensive coronary care unit (ICCU) with ACS
which includes 38 ST-elevation myocardial infarction (STEMI), 2 non-ST STEMI, and 10 unstable angina patients. Fifty healthy
gender- and age-matched subjects were taken as control group. The fasting venous sample was collected. plasma Lp(a) total
cholesterol (TC), triglycerdies (TGL) and high density lipoprotein (HDL) estimated. LTI was calculated by the product of TC,
TGL, and Lp(a) divided by high-density lipoprotein and compared between two groups.
Results: The mean Lp(a), LTI were significantly elevated in study group compared to control group (P = 0.0001).
Conclusion: Elevated LTI depicts it as a risk factor in ACS and a promising atherogenic index for assessment in ACS compared
to other lipid parameters
Item Type: | Article |
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Uncontrolled Keywords: | Acute coronary syndrome, Coronary artery disease, Lipid parameters, Lipid tetrad index, Lipoprotein (a) |
Depositing User: | Mr Team Mosys |
Date Deposited: | 10 Aug 2022 05:39 |
Last Modified: | 10 Aug 2022 05:39 |
URI: | http://ir.psgcas.ac.in/id/eprint/1434 |