Brindha, Durairaj and Santhi, Ramalingam and Aparna Pragadeaswari, K and Valarmathi, R (2018) Antioxidant, Free Radical Scavenging and Antibacterial Potential of Biosynthesized Zinc Oxide Nanoparticles of Carica Papaya Seeds. International Journal for Research in Applied Science & Engineering Technology (IJRASET) ISSN: ; IC Value: 45.98; SJ Impact Factor: 6.887 Volume 6 Issue IV, April 2018- Available at, 6 (IV). pp. 3011-3017. ISSN 2321-9653

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Introduction: Green synthesis of zinc oxide nanoparticles (ZnO NPs) is ecofriendly, inexpensive and nontoxic when
compared to physical and chemical methods. In this paper, we report the synthesis and characterization of ZnO NPs using
Carica papaya seeds extract.
Methodology: Preliminary phytochemical analysis were carried out using standard procedures with different solvents like
chloroform, acetone, ethanol and aqueous. The enzymic and nonenzymic antioxidants present in Carica papaya seeds were
determined. Free radical scavenging potential of ZnO NPs was assessed by various methods namely DPPH, hydroxyl radical,
hydrogen peroxide, superoxide and nitric oxide scavenging assays. Moreover, total antioxidant activity was evaluated by
phosphomolybdenum method. The antibacterial activity against the Carica papaya seed extract was also determined by agar well
diffusion method. Result: Among the different extracts used, aqueous extract showed more positive results and hence it was
used for further studies. The maximum absorbance of ZnO NPs was noticed at 274 nm in the UV-Visible absorption spectrum.
The free radical scavenging activity of biosynthesized ZnO NPs was increased in dose dependent manner. The maximum zone of
inhibiton was noticed in Escherichia coli.
Conclusion: The results revealed that zinc oxide nanoparticles of Carica papaya seed extract possess potent antioxidant and
antibacterial properties.

Item Type: Article
Uncontrolled Keywords: Zinc oxide nanoparticles, Carica papaya, UV-Visible spectroscopy, Escherichia coli
Depositing User: Mr Team Mosys
Date Deposited: 18 Aug 2022 05:22
Last Modified: 18 Aug 2022 05:22

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