Ashwini Malla and Balaji Muralikrishnan (2025) Bioprospecting Actinomycetes from the Rhizosphere of Piper nigrum: Potential and Challenges. Bioprospecting Actinomycetes from the Rhizosphere of Piper nigrum: Potential and Challenges, 20 (11). pp. 396-401.

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Abstract

This prospective review explores the biotechnological
potential of actinomycetes isolated from the
rhizospheres of Piper nigrum L. which is commonly
known as black pepper. Actinomycetes are Gram�positive filamentous bacteria that are well known for
their ability to produce a plethora of bioactive
compounds, including antibiotics. The rhizosphere, a
nutrient-rich zone surrounding plant root, offers a
unique microenvironment that fosters the growth of
diverse actinomycetes with unique metabolic
capabilities. This review underscores the significance
of these microorganisms in soil ecosystems,
highlighting their crucial role in the discovery of novel
antibiotics in the context of rising antimicrobial
resistance.
Furthermore, it delves into the challenges associated
with bioprospecting actinomycetes including
difficulties in isolation and cultivation, genetic
manipulation and the complex, time-intensive pipeline
required to develop and commercialize new antibiotics.
Through addressing these challenges, this review
provides insights into improving strategies for
harnessing the full potential of rhizosphere
actinomycetes in antibiotic discovery

Item Type: Article
Uncontrolled Keywords: Actinomycetes, Antibiotics, Bioprospecting, Piper nigrum, Rhizosphere.
Divisions: PSG College of Arts and Science > Department of Biotechnology
Depositing User: Dr. B Sivakumar
Date Deposited: 01 Apr 2026 06:58
Last Modified: 01 Apr 2026 07:10
URI: https://ir.psgcas.ac.in/id/eprint/2764

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