Priya, K (2013) Cyathula prostrata: A potent source of anticancer agent against daltons ascites in Swiss albino mice. Asian Pacific Journal of Tropical Medicine. pp. 776-779. (In Press)

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Abstract

Objective: To evaluate the anticancer activity of the methanolic extract of Cyathula prostrata in Ehrlich ascites carcinoma (EAC)-bearing mice with methotrexate as positive control in the advanced stage of tumorigenesis. Methods: EAC was induced in swiss albino mice by injecting
106 cell/mL of tumor cell suspension intraperitoneal. The methanolic extract of Cyathula prostrata effect on the tumor cell viability, DNA fragmentation and MTT assay were carried out. Results: Methanolic extract attenuated percentage increased in the cell survival time when compared to
control group. However, the effect was less than that of methotrexat. Methotrexat and the extracts reversed the tumor-induced alterations in DNA fragmentation and MTT assay. Conclusions: The present study suggests that the methanol extract of Cyathula prostrata has significant anticancer activity and that is comparable to that of methotrexate.

Item Type: Article
Uncontrolled Keywords: Cyathula prostrata MTT Cancer Ehrlich ascites carcinoma
Depositing User: Mr Team Mosys
Date Deposited: 25 Jul 2022 05:30
Last Modified: 25 Jul 2022 06:18
URI: http://ir.psgcas.ac.in/id/eprint/1351

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