Victor Arokia Doss, D and Sowndarya, R and Sandhiya, S Antidepressant activity of Cucumis melo Fruit Extract in Stress Induced Rats. PSGCAS Search: A Journal of Science and Technology, 3 (1). pp. 58-62. ISSN 2349 – 5456

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Abstract

Cucumis melo (Cucurbitaceae), from many centuries have been used in Indian traditional medicinal system for the
treatment of various disorders such as cardioprotective aid and in obesity. The present study was to investigate the
possible antidepressant activity of Cucumis melo (CM) fruit extract in stress induced rats. Hydroethanolic extract of
CM was quantified for phenolic content by Folin-Ciocalteau’s method. CUMS protocol was employed to induce
stress in rats. CM (50 and 100mg/kg,bw) and Fluoxetine (20mg/kg,bw) was administered during 21day stress
exposure period. Antidepressant activities were assessed by Forced Swimming Test (FST). The results conclude that
CM possesses anti-stress and moderate anxiolytic activity which may be due, in part, to its antioxidant effect.

Item Type: Article
Uncontrolled Keywords: Cucumis melo, antidepressant activity, antioxidant effect
Depositing User: Mr Team Mosys
Date Deposited: 12 Aug 2022 07:16
Last Modified: 12 Aug 2022 07:16
URI: http://ir.psgcas.ac.in/id/eprint/1456

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