Brindha, Durairaj and Santhi, Ramalingam and Chidambaramoorthy, M (2018) In Vitro Anticancer Potential Of Hydroethanolic Extract Of Canthium Coromandelicum Against Neuroblastoma SHSY5Ycell Line. International Journal for Science and Advance Research In Technology, 4 (4). pp. 862-864. ISSN 2395-1052

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Abstract

Cancer is an uncontrollable growth of the living
cells and it is a major public health problem in worldwide and
affects the functioning of many parts of the body. Plant based
medicine are used in cancer prevention and treatment in many
countries. The in vitro anticancer assay was measured by
MTT assay against neuroblastoma SHSY5Y cancer cell line.
The hydroethanolic extract of Canthium coromandelicum
moderately inhibit neuroblastoma SHSY5Y cancer cell line
growth. Measurements were performed and the concentration
required for 50% inhibition of viability (IC50) was determined
graphically. The effects of the samples on the proliferation of
neuroblastoma SHSY5Y cell line was expressed as the % cell
viability. From the graphs the concentration of
hydroethanolic extract yields the values of LC50 (46%
mortality) as 50μg/ml respectively for Canthium
coromandelicum. In the same way the concentration at which
99% mortality occurs for the hydroethanolic extract are
obtained from the graphs and the values have been found to be
5μg/ml for Canthium coromandelicum.

Item Type: Article
Uncontrolled Keywords: Hydroethanolic extract, Canthium coromandelicum, MTT Assay, Neuroblastoma SHSY5Y cell line.
Depositing User: Mr Team Mosys
Date Deposited: 18 Aug 2022 04:42
Last Modified: 18 Aug 2022 04:42
URI: http://ir.psgcas.ac.in/id/eprint/1489

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