Deepa, S and Syed Ibrahim, K (2022) Efficiency of Coriandrum sativum (Linn.) and Petroselinum crispum (Mill.) in Enhancing Iron Absorption: An In Silico and In Vitro Approach. Evidence-Based Complementary and Alternative Medicine: 7359081. pp. 1-8.

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Abstract

Coriandrum sativum (Linn.) and Petroselinum crispum (Mill.) are the common herbs used for culinary purposes in daily life. �e
chlorophyll pigment in plants is being identi�ed with various medicinal values, whereas iron is an essential micronutrient for the
proper metabolism of the human body. �e current research has been aimed at predicting the role of C. sativum and P. crispum in
enhancing iron absorption via an in vitro approach. C. sativum and P. crispum have been analyzed for their capability of being a
source of chlorophyll and iron concentration. �e extracts prepared from solvents like carbinol, petroleum ether, and water were
subjected to the identi�cation of phytoconstituents through gas chromatography-mass spectrometry analysis, and the identi�ed
compounds were subjected to in silico studies against the iron-binding receptor, transferrin, to depict the binding a�nity of the
identi�ed compounds. �e carbinol extract was then put through in vitro analytical studies in Caco2 cell lines with a concentration
of 500 µg/ml. Current research has shown that the leaves of C. sativum and P. crispum are an excellent source of chlorophyll and
iron and has also suggested that these herbs e�ciently enhance the absorption of iron in human intestinal cells.

Item Type: Article
Divisions: PSG College of Arts and Science > Department of Botany
Depositing User: Mr Team Mosys
Date Deposited: 27 Sep 2022 07:53
Last Modified: 27 Sep 2022 07:53
URI: http://ir.psgcas.ac.in/id/eprint/1554

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