Subhashini, M (2023) Green synthesis of nanohydroxy apatite using Calotropis procera and Wrightia tinctoria plant latex serum extract for biomedical application. Biomass Conversion and Biorefnery.

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Abstract

Medical textiles have become increasingly important and extend the strong protection role in the healthcare industry. The goal
of this study was to improve conventional cotton gauze into advanced biomedical specifcations with antimicrobial activity.
The cotton gauze fabrics were modifed by in situ wet chemical precipitation of hydroxyapatite nanoparticles (HAp NP) with
Calotropis procera and Wrightia tinctoria plant latex serum extract. The developed nanoparticles were initially examined by
UV–visible spectrophotometer with maximum absorbance peak at 274 nm for Calotropis procera and 286 nm for Wrightia
tinctoria. To determine the lattice formation and average crystal size, X-ray difraction (XRD) study was done and the size
was observed as 31.13 μm and 29.18 μm for Calotropis procera and Wrightia tinctoria serum extract hydroxyapatite nanoparticles respectively. Fourier transform infra-red spectroscopy (FTIR) confrmed the presence of functional groups such
as the carbonate and phosphate group in both the developed nanoparticle as they are the important agents for forming Hap.
The scanning electron microscope (SEM) result confrms the developed nanoparticle was hexagonal in shape with polycrystalline morphology. Deposition of Calotropis procera and Wrightia tinctoria HAp NP onto cotton gauze fabrics resulted
in signifcant antimicrobial activity with zone of inhibition against Candida albicans, Aspergillus niger, Staphylococcus
aureus, and Escherichia coli. Hence, the present work highlighted the development of plant extract-mediated hydroxyapatite
nanoparticles having excellent antibacterial properties and it can be recommended for medical application

Item Type: Article
Uncontrolled Keywords: Hydroxyapatite nanoparticle · Plant latex serum · X-ray difraction · UV–visible spectrophotometer · FTIR and SEM
Divisions: PSG College of Arts and Science > Department of Microbiology
Depositing User: Mr Team Mosys
Date Deposited: 03 Jul 2023 09:47
Last Modified: 03 Jul 2023 09:47
URI: http://ir.psgcas.ac.in/id/eprint/1945

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