Surya Sivakumar and Boobal Rangaswamy and Lathika Shanmugam and Kamalesh Marudhachalam (2025) Phytochemical mediated zinc oxide nanoparticles from Euphorbia antiquorum: Synthesis, characterization & antibacterial activity. Phytochemical mediated zinc oxide nanoparticles from Euphorbia antiquorum: Synthesis, characterization & antibacterial activity, 8 (100210). pp. 1-10. ISSN 2949-8295

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Abstract

The plant extract of Euphorbia antiquorum was utilized to perform a green synthesis of zinc oxide nanoparticles
(ZnO NPs). The phytochemical components of the nanoparticles were subsequently examined. The ZnO NPs
produced through biosynthesis were analyzed using several spectroscopic methods. The plant extract revealed
the existence of alkaloids, tannins, flavonoids, terpenoids, gums, and mucilages, which played a role in the
production of ZnO NPs by decreasing metal ions and ensuring the stability of the process. The Fourier-transform
infrared spectroscopy (FTIR) revealed the unique spectra associated with ZnO NPs at a wavenumber of
455.20 cm
1
. The nanoparticles were observed to have a nanoflake structure by analysis with the Field Emission
Scanning Electron Microscope (FE-SEM). The average size of the crystallites was determined to be 37 nm using X-
ray diffraction (XRD) patterns. The Energy-dispersive X-ray spectroscopy (EDX) spectra of ZnO NPs confirmed
the nanoparticles production with very few impurities. The antibacterial efficacy of the synthesized NPs was
assessed by determining the Minimum Inhibitory Concentration (MIC) and Minimum Bacterial Concentration
(MBC) against E. coli, Pseudomonas sp., Vibrio sp., and Bacillus sp. The presence of phytochemicals and the activity
against microorganisms evidenced the importance of NPs to prevent infection, promote wound healing and to
treat diseases. This study determines that ZnO NPs possess substantial antibacterial properties against diverse
aquatic pathogens, presenting them as a viable substitute for conventional antibiotics

Item Type: Article
Uncontrolled Keywords: Nanoparticles ZnO Green synthesis Antibacterial activity
Divisions: PSG College of Arts and Science > Department of Biochemistry
Depositing User: Dr. B Sivakumar
Date Deposited: 11 Dec 2025 07:06
Last Modified: 11 Dec 2025 07:06
URI: https://ir.psgcas.ac.in/id/eprint/2583

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