Krishnamoorthy Bellie Sundaram (2022) BIOLOGICAL STUDIES OF 4-AMINO BENZAMIDE DERIVED 1,2,3-TRIAZOLE LINKED CHALCONE AND ITS PYRAZOLINE DERIVATIVES. BIOLOGICAL STUDIES OF 4-AMINO BENZAMIDE DERIVED 1,2,3-TRIAZOLE LINKED CHALCONE AND ITS PYRAZOLINE DERIVATIVES, 15 (9). ISSN 2455-3891

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Abstract

Objectives: The present work planned to investigate the anti-bacterial, anti-fungal, and anti-oxidant activity against 4-amino benzamide derived
1,2,3-triazole linked chalcone and pyrazoline derivatives.
Methods: Anti-microbial activity for pyrazoline derivatives was accomplished by serial dilution method. The test organisms of bacterial strains
were (Enterococcus faecalis, Staphylococcus aureus, Klebsiella pneumoniae, and Pseudomonas fluorescence) and the fungal cultures (Aspergillus niger,
Aspergillus terreus, and Trichoderma harzanium). The method used in the anti-oxidant activity is 2,2-diphenyl-1-picrylhydrazyl (DPPH) and nitric
oxide scavenging method.
Results: All the compounds showed good to moderate anti-bacterial and anti-fungal activities. The results of IC50 values showed lower potent
inhibition activity with DPPH and higher potent inhibition activity in nitric oxide scavenging method.
Conclusion: All the compounds had exhibited capricious growth inhibitory effect on anti-bacterial, anti-fungal, and anti-oxidant activities.
Keywords: 1,2,3-triazole, Chalcone, Pyrazoline, Anti-microbial activity and anti-oxidant activity

Item Type: Article
Uncontrolled Keywords: 1,2,3-triazole, Chalcone, Pyrazoline, Anti-microbial activity and anti-oxidant activity
Divisions: PSG College of Arts and Science > Department of Chemistry
Depositing User: Dr. B Sivakumar
Date Deposited: 13 Mar 2026 04:27
Last Modified: 13 Mar 2026 04:27
URI: https://ir.psgcas.ac.in/id/eprint/2703

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