Krishnamoorthy Bellie Sundaram (2025) Therapeutic Potential of Gut Microbiota Modulation in Non�Communicable. Therapeutic Potential of Gut Microbiota Modulation in Non�Communicable Dise, 25 (5). pp. 498-512. ISSN 0023:4923

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Abstract

The human gut microbiota is essential to human well-being which contains a
complex set of microorganisms that performs important bodily activities and maintains
homoeostasis within the body. Among the most potent factors influencing the composition and
activities of the gut microbiota is diet. The intricate interactions between the immune system
and the intestinal barrier underscore the crucial role that nutrition plays in both the aetiology
and management of various illnesses. The term dysbiosis refers to alterations and imbalances
in the makeup of the gut microbiota, which can result in a variety of disorders. Maintaining
good health and preventing non-communicable diseases (NCDs) depend heavily on diet. Non�communicable illnesses are prevalent throughout the world and account for 41 million annual
deaths, or 74% of all fatalities globally. Noncommunicable diseases (NCDs) comprise cancer,
cardiovascular disorders, cognitive impairments, and metabolic disorders and a number of
factors, such as the environment, microbes, the surrounding area, and food, contribute to the
spread of NCDs. Globally, NCDs account for the majority of death cases. Diet is a major factor
in controlling the variety and abundance of gut microorganisms. Diet is also thought to play a
major role in the establishment of the gut microbiota, which contributes to the pathophysiology
of non-communicable diseases. This review aims to provide an overview of the therapeutic
benefits of diets on different NCDs and their function in gut microbiota modulation. The
importance of nanoparticles in the modelation of gut microbiota and their effects also
addressed.

Item Type: Article
Uncontrolled Keywords: Non-communicable diseases; diabetes; cancer; gut microbiome; diet, nano�materials;
Divisions: PSG College of Arts and Science > Department of Chemistry
Depositing User: Dr. B Sivakumar
Date Deposited: 13 Mar 2026 05:44
Last Modified: 13 Mar 2026 05:44
URI: https://ir.psgcas.ac.in/id/eprint/2706

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