Brindha Durairaj and Ravikumar Manish (2019) Zebrafish: An In Vivo Model for the Study of Therapeutic Targets of Epilepsy. Zebrafish: An In Vivo Model for the Study of Therapeutic Targets of Epilepsy, 6 (4). pp. 190-196.

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Abstract

Epilepsy is a common neurological disorder due to excessive brain cell activity. It is characterized by unpredictable seizures resulting in cognition. The release of abnormal electric discharge in the regions of the brain causes epileptic seizures. Neurotransmitters play an important role in normal functioning of the brain and thus alteration of these neurotransmitters are associated with epilepsy. Zebrafish model have recently become a focus for various neurological disorders because of its high genetic similarity when compared with those of humans. Zebrafish can be grown in large numbers and their embryos are optically clear allowing examination of individual genes. This review will look at the utility of the zebrafish in the study of various therapeutic targets of epilepsy such as GABA (gamma-aminobutyric acid), AMPA, NMDA (N-methyl-d-aspartate), histamine H3, and phosphodiesters.

Item Type: Article
Uncontrolled Keywords: epilepsy; seizures; neurotransmitters; zebrafish; therapeutic targets
Divisions: PSG College of Arts and Science > Department of Biochemistry
Depositing User: Dr. B Sivakumar
Date Deposited: 25 Mar 2026 10:10
Last Modified: 25 Mar 2026 10:10
URI: https://ir.psgcas.ac.in/id/eprint/2740

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