Kathiravan, S (2025) Clinical Significance of N-terminal pro B-type Natriuretic Peptide (NT-proBNP) in Heart Failure: A Comprehensive Review. Clinical Significance of N-terminal pro B-type Natriuretic Peptide (NT-proBNP) in Heart Failure: A Comprehensive Review, 2. pp. 37-40. ISSN 0976-4585;

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Abstract

Heart failure (HF) is a prevalent and debilitating cardiovascular condition that demands precise diagnostic tools and
personalized management strategies. In this review, we synthesize findings from seminal research articles to elucidate
the clinical significance of NT-proBNP in HF diagnosis and management. Heart failure, a condition characterized by
impaired cardiac function, imposes a significant global health burden. Timely and precise diagnosis is paramount for
effective management. Among the numerous diagnostic and prognostic markers available, N-terminal pro B-type
natriuretic peptide (NT-proBNP) has emerged as a prominent biomarker in the domain of heart failure. NT-proBNP,
released by ventricular myocytes in response to myocardial stress, serves as a discriminative diagnostic tool. Elevated
serum NT-proBNP levels provide sensitive and specific indications of myocardial stress, facilitating the rapid
identification of heart failure cases. Its unique capacity to differentiate heart failure from conditions with similar clinical
presentations bolsters its diagnostic significance

Item Type: Article
Uncontrolled Keywords: NT-proBNP, Atrial natriuretic peptide, Heart failure, biomarker and monitoring
Divisions: PSG College of Arts and Science > Department of Biochemistry
Depositing User: Dr. B Sivakumar
Date Deposited: 26 Mar 2026 08:10
Last Modified: 26 Mar 2026 08:10
URI: https://ir.psgcas.ac.in/id/eprint/2742

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