Vino Udappusamy and RajanThinakaran (2023) The antibacterial, antioxidant, and antiproliferative effects of guava fruit peel extracts against HT29 colon cancer cell lines”. “The antibacterial, antioxidant, and antiproliferative effects of guava fruit peel extracts against HT29 colon cancer cell lines” Vino Udappusamy and RajanThinakaran, 12 (4). pp. 2998-3016.

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Abstract

The study used quantitative ecological approaches to quantify the number of
species, variety, and how the environment affects plant evolution through time. Psidium
guajava has many biological characteristics, including antimicrobial and anticancer
properties. This project intends to uncover, define, and assess phytochemical substances as
colon cancer antioxidants. The fruit peel extract contained alkaloids (35.5 mg/g), flavonoids
(14 mg/g), phenols (39.5 mg/g), and tannins (35 mg/g). Fourier Transform Infrared
Spectroscopy identified functional groups in ethanolic guava peel extract. Guava fruit peel
extract's antimicrobial properties were examined. Staphylococcus aureus and Enterobacter
aerogenes were particularly sensitive. Psidium guajava peel extract inhibited 76.29% of free
radicals at 500 mg/ml. Psidium guajava extract was non-toxic to normal cells but harmful to
HT29 colon cancer cells (IC50 = 75.51 µg/ml). According to the results, fruit peel extract
could treat colon cancer.

Item Type: Article
Uncontrolled Keywords: : Psidium guajava, colon cancer, antimicrobial activity, Antioxidant activity
Divisions: PSG College of Arts and Science > Department of Biochemistry
Depositing User: Dr. B Sivakumar
Date Deposited: 27 Mar 2026 04:23
Last Modified: 27 Mar 2026 04:23
URI: https://ir.psgcas.ac.in/id/eprint/2747

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